Clinical-immunological assessment of therapy effect of the neuro-sensory-motor integration program of reflex patterns in airway chronic inflammatory diseases

Airway chronic inflammatory diseases and recurrent exacerbations are mainly caused by damage of immune regulation mechanisms.Treatment of chronic inflammatory diseases of respiratory tract in children and adults was carried out by combining complimentarytherapy using the method of neuro-sensory-motor reflex patterns integration (NRI), which works with primary motor systemactivation and conventional treatment; the parameters of the immune status and the cortisol level in children suffering from of arecurrent obstructive bronchitis are studied, as well as the assessment of therapy efficiency based on NRI method is done. It isestablished that combining the therapy using primary motor system/reflex integration with the conventional treatment allowscorrecting the immune system mechanisms’ damage to a certain extent mainly to normalize the amount of Т lymphocytes (CD3, CD4,CD8) and NK-cells, metabolic function of leukocytes, the level of regulatory and anti-inflammatory cytokines. The therapy based onneuro-sensory-motor reflex patterns integration (NRI) improves the effect of standard therapy on immune system cells andstrengthens the polarization of immune response to Th-1 type. It decreases the frequency of airway viral inflammatory diseases, leadsto positive dynamics of chronic respiratory diseases and prolongs their remission.